艾昆纬-自信而专注地创新-通过利用新的工具和方法，提高设计、规划和试验交付的可预测性和质量（英）

White PaperInnovating with Confidence and Focus Enhance predictability and quality in design, planning and trial delivery by leveraging novel tools and approachesRAJA SHANKAR, VP, Machine Learning, IQVIA STEPHEN HAMPTON, Director, Enterprise Architecture – Generative AI, IQVIAPart 2 of a 4-part series highlighting key innovations in clinical researchTable of contentsThe foundations of confidence: preparation and predictability 3The evolution towards prescriptive analytics 3More confident choices: key innovations in planning and design 4Advancements in clinical development planning 5Incorporating IQVIA Healthcare-grade AI® into pre-clinical analysis 5I. Understanding the asset’s properties and clinical landscape 5II. AI-powered insights to drive protocol optimization 6III. Rapidly generating scenarios for enrollment strategies 7IV. Accelerating site startup with targeted regulatory intelligence 8Looking ahead: the increasing role of agentic AI 8Conclusion 8About the authors 9 iqvia.com/rds | 3“With more advanced, cutting-edge technologies and tools increasingly available to better inform decisions, sponsors and their CRO partners can enhance the predictability of success and quality across design, planning and trial management.”Life involves risk, there’s no getting around it. In every aspect of our lives — whether it’s buying a car, starting a new career or making an investment, there is always a chance that things may not turn out as expected. To navigate successfully through our daily lives, we must prepare for unforeseen events and have contingency planning in place. The more informed our choices, the more likely we are to succeed.Similarly, in today’s rapidly-evolving clinical research ecosystem, safeguarding against risk through careful planning and management remains the cornerstone of successful design and delivery — ensuring the safety of trial participants, protecting data quality, achieving milestones in a timely fashion, optimizing patient recruitment and retention, and enhancing end-to-end efficiencies.And today, with highly advanced, cutting-edge technologies and tools increasingly available to better inform decisions, sponsors and their CRO partners can enhance the predictability of success and quality across design, planning and trial management — more so than ever before.This paper provides an overview of some key areas of innovation and technologies that are empowering better decision-making in early planning, design and across the clinical development continuum. By judiciously leveraging these advancements — in combination with improved data generation, expertise and domain experience — sponsors and CROs can have greater confidence in harnessing innovation to achieve better outcomes in their clinical trial programs.The evolution towards prescriptive analyticsBefore exploring specific methods being used to improve clinical trial predictability, it’s important to consider the evolution of advanced analytics in clinical trials