Citeline RD2025-2025医药研发年度回顾-英文版

WHITE PAPERFind out what’s in and out of fashionin drug development with our analysisof this year’s key pipeline trends.Powered by PharmaprojectsWhy did Pfizer regain its crown?How come everybody's looking at China?Welcome 0303Introduction: Total Pipeline Size 05 05 Pharma has more material than ever before Following the Pattern: The 2025 Pipeline by Phase of Development 07 07 Can the industry cut its clinical coat according to its cloth? Top Companies 10 10 Vintage names look solid, while boutique firms flourish Therapies and Diseases 18 18 Cancer still en vogue, but have we reached peak oncology? Regional Variations 2828The leading players in key markets, and the varying styles of drug R&DMechanisms and Targets 4747Immuno-oncology continues to be the trend everyone is followingTypes of Pipeline Drugs 5252Biotech struts its stuff on the pharma catwalk What’s the Forecast for Pharma? 6161Is the pharma industry still wearing the trousers, or might it be caught with its pants down? About the Author 6666ContentsContentsWelcome to Pharmaprojects’ 2025 review of trends in pharmaceutical R&D Welcome to Pharmaprojects’ 2025 review of trends in pharmaceutical R&D. For over 30 years now, I’ve been taking an annual look at the evolution of pharma R&D, and in this article, I’ll investigate how fashions are changing in the industry at the start of 2025. We’ll assess industry trends by examining the pipeline by company, therapeutic area, disease, target, and drug type, using data primarily from Pharmaprojects, part of the Citeline suite of products, which has been tracking global drug development since 1980. This report will be followed up by our annual supplement reviewing the New Active Substance (NAS) launches for the year just passed. But here, we’ll roll up our sleeves to examine how pharma R&D is changing, look at what’s becoming a la mode and what’s now decidedly last season, and try to determine where the industry is dressed for the occasion and where it’s looking like vintage trying to be vogue. Hopefully, it will help you to see what’s in and out of fashion in the world of drug development.Regular readers of this report (which has been running since 1993, so is presented here in its 33rd edition) will know that in recent years, I’ve threaded a different theme through each edition, to highlight points, to draw analogies, and to add a little character into what could otherwise be a rather lengthy narrative through a parade of statistics, charts, and tables — drabber than a bunch of dusty hand-me-downs at the back of a charity shop. Themes selected so far have included astronomy, movies, the natural world, music, food and drink, science fiction, travel, literature and last year, weather. This year, as those of you who are on trend may have guessed, I’ve hung my rather jaunty hat on the topic of fashion and clothing. As with healthcare, like it or not, it’s something that affects us all, and where things come in and