欧洲疾控中心-2024年潜在人畜共患甲型流感病毒分子检测、亚型和特征的外部质量评估（英）

External quality assessment for molecular detection, subtyping and characterisation of potentially zoonotic type A influenza viruses, 2024An ECDC-funded AURORAE laboratory support activity for national influenza centres/reference laboratories in the European Union/European Economic Area (EU/EEA), Western Balkan countries and TürkiyeASSESSMENTECDC ASSESSMENT External quality assessment for molecular detection, subtyping and characterisation of potentially zoonotic type A influenza viruses, 2024 An ECDC-funded AURORAE laboratory support activity for national influenza centres/reference laboratories in the European Union/European Economic Area (EU/EEA), Western Balkan countries and Türkiye EQA for molecular detection, subtyping and characterisation of potentially zoonotic type A influenza viruses ECDC ASSESSMENT ii This report was commissioned by the European Centre for Disease Prevention and Control (ECDC), Framework Contract Number – ECDC/2022/001, LOT 1: Centralised laboratory support, coordinated by Angeliki Melidou (ECDC) and Eeva Broberg (ECDC) and produced by Adam Meijer, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. Authors Adam Meijer, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands. Acknowledgements We would like to thank Gabriel Goderski and Sharon van den Brink and the associated team of technicians for panel preparation and internal quality control of the final panel specimens at the Department of Emerging and Endemic Viruses, Centre for Infectious Diseases Research, Diagnostics and Laboratory Surveillance, RIVM, Bilthoven, the Netherlands, and Ingmar Visser, RIVM, for assistance in data analysis. We thank patients and their treating physicians and diagnostic laboratories for the possibility to use the human seasonal and zoonotic swine type A influenza viruses detected in the clinical specimens submitted to the RIVM for the purpose of this European External Influenza Quality Assessment Programme (EEIQAP) study. Thank you to Ron Fouchier and Oanh Vuong, Erasmus Medical Centre (Erasmus MC), Department Viroscience, Rotterdam, the Netherlands, for providing avian influenza virus strains. Thanks also to Étienne Simon-Lorière, Institut Pasteur, Paris, France, for providing the A(H3N2) swine influenza virus. Pretesting of the panel with specimens labelled in random order was performed at Centre National de Référence Virus des Infections Respiratoire, Laboratoire de Virologie, Institut des Agents Infectieux, Lyon, France, with special thanks to Bruno Lina, Martine Valette and Vanessa Escuret and Institut Pasteur, Paris, France, with special thanks to Étienne Simon-Lorière. Panel distribution and data services were provided by Quality Control for Molecular Diagnostics (QCMD), Glasgow, UK, with special thanks to Elaine McCulloch, Lynette Walsh, Alan Flisch and Richard Bache. We thank Alice Fusaro, European Union Reference Laboratory for Avian Inf